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Paul Siegel

Univ. Distinguished Prof. Emeritus of Animal & Poultry Sci.

Genetics


BS - 1953, University of Connecticut
MS - 1954, Kansas State University
PhD - 1956, Kansas State University

Publications (2011-2013):


Besnier, F., P. Wahlberg, L. Ronnegard, W. Ek, L. Andersson, P. B. Siegel, and O. Carlborg. 2011. Fine
mapping and replication of QTL in outbred chicken advanced intercross lines. Gen. Sel. Evol. 43:3.

Xu, P., P. B. Siegel, and D. M. Denbow. 2011. Genetic selection for body weight in chickens has altered
responses of the brain’s AMPK system to feed regulation of ghrelin, but not obestatin. Behav. Brain Res.221:216-226.

Xu, P., P. B. Siegel, D. M. Denbow. 2011. AICAR compound C regulates food intake independently of
AMP-activated protein kinase in lines of chickens selected for high or low body weight. Comp. Biochem. Physiol. 159:401-412.

Dorshorst, B. J., P. B. Siegel, and C. M. Ashwell. 2011. Genomic regions associated with antibody
response to sheep red blood cells in the chicken. Anim. Gen. 42:300-308.

Smith, M., B. C. Prall, P. B. Siegel, and M. A. Cline. 2011. The threshold of insulin-induced hypophagia
is lower in chicks selected for low rather than high juvenile body weight. Behav. Brain Res. 216:719-722.

Pettersson, M., F. Besnier, P. B. Siegel, and O. Carlborg. 2011. Replication and explorations of high-
order epistasis using a large advanced intercross line pedigree. PLoS Genetics 7:e1002180.

Wu, G. Q., P. B. Siegel, E. R. Gilbert, N. Yang, and E. A. Wong. 2011. Expression profiles of
somatotropic axis genes in lines of chickens divergently selected for 56-day body weight. Anim. Biotech. 22:100-110.

Siegel, P. B., S. J. Gustin, M. N. Katanbaf. 2011. Motor ability and self-selection of an analgesic drug by
fast-growing chickens. J. Appl. Poult. Res. 20:249-252.

Gaydos, J. K., J. G. Massey, D. M. Mulcahy, L. A. Gaskins, D. Nysewander, J. Evenson, P. B. Siegel, and
M. H. Ziccardi. 2011. Short-term survival and effects of transmitter implantation into Western Grebes using a modified surgical procedure. J. Zoo and Wildlife Med. 42:414-425.

Dunnington, E. A., N. O’Sullivan, and P. B. Siegel. 2011. Early and late feathering in chickens: Gender
determination in chicks. Anim. Sci. Image Gallery (PowerPoint presentation designed for high
school and college genetics courses). [NAL 5150]: http://anscigallery.nal.usda.gov/browse.php.

Ka, S., F. W. Albert, D. M. Denbow, S. Paabo, P. B. Siegel, L. Andersson, and F. Hallbook. 2011.
Differentially expressed genes in hypothalamus in relation to genomic regions under selection in two chicken lines resulting from divergent selection for high or low body weight. Neurogenetics 12: 211-221.

Blevins, S., P. B. Siegel, D. J. Blodgett, M. Ehrich, and R. M. Lewis. 2012. Liver enzymes in White
Leghorns selected for the SRBC immune response. Poult. Sci. 91:322-326.

Sumners, L. H., C. M. Cox, S. Kim, J. E. Salevsky, P. B. Siegel, and R. A. Dalloul. 2012. Immunological
responses to Clostridium perfringens alpha-toxin in two genetically divergent lines of chickens as influenced by major histocompatability genotype. Poult. Sci. 91:592-603.

Ek, W., S. Marklund, A. Ragavendran, P. Siegel, W. Muir, and O. Carlborg. 2012. Generation of
multi-locus chicken introgression line to study the effects of genetic interactions on metabolic phenotypes in chickens. Frontiers in Genet. Arch.10.3389/fgene.2012.00029.

Zhao, X. L., C. F. Honaker, and P. B. Siegel. 2012. Phenotypic responses of chickens to long-term
selection for high or low antibody titers to sheep red blood cells. Poult. Sci. 91:1047-1056.

Yalcin, S., S. Ozkan, P. Siegel, C. Yenisey, and M. Aksit. 2012. Manipulation of incubation temperatures
to increase cold resistance of broilers: Influence on embryo development, organ weights, hormones, and body composition. J. Poult. Sci. 49:133-139.

Albrecht, H. N., P. B. Siegel, F. W. Pierson, M. L. McGilliard, and R. M. Lewis. 2012. Reproductive
soundness is higher in chickens selected for low as compared to high antibody response. Poult. Sci. 91:1796-1803.

Zhao, X. L., P. B. Siegel, Y. P. Liu, Y. Wang, E. R. Gilbert, Q. Zhu, and L. Zhang. 2012. Housing system
affects broiler characteristics of local Chinese breed reciprocal crosses. Poult. Sci. 91:2405-2410.

Dunnington, E. A., E. R. Gilbert, and P. B. Siegel. 2012. Growth in chickens: Glucose tolerance. Anim.
Sci. Image Gallery (PowerPoint presentation designed for high school and college genetics courses). [NAL 5174]: http://anscigallery.nal.usda.gov/browse.php.

Dunnington, E. A., E. R. Gilbert, and P. B. Siegel. 2012. Growth in chickens: Insulin sensitivity. Anim.
Sci. Image Gallery (PowerPoint presentation designed for high school and college genetics courses). [NAL 5175]: http://anscigallery.nal.usda.gov/browse.php.

Albrecht, H. N., P. B. Siegel, F. W. Pierson, and R. M. Lewis. 2012. Egg quality traits differ in hens
selected for high as compared to low antibody response to sheep red blood cells. Poult. Sci. 91:3025-3031.

Yalcin, S., N. Bagdathoglu, C. Yenisey, P. B. Siegel, S. Ozkan, and M. Aksit. 2012. Effect of
manipulation of incubation temperatures on fatty acid profiles and antioxidant enzyme activities in meat-type chicken embryos. Poult. Sci. 91:3260-3271.

Alvarez-Castro, J. M., A. LeRouzic, L. Andersson, P. B. Siegel, and O. Carlborg. 2012. Modeling of
genetic interactions improves prediction of hybrid patterns – a case study in domestic fowl. Genetics Research 94:255-266.

Newmyer, B. A., W. Nandar, R. I. Webster, E. Gilbert, P. B. Siegel, and M. A. Cline. 2013. Neuropeptide
Y is associated with changes in appetite-associated hypothalamic nuclei but not food intake in a hypophagic avian model. Behav. Brain Res. 236:327-331.

Zhao, L., G. Wang, P. B. Siegel, C. He, W. Zhao, Z. Zhai, F. Tian, J. Zhao, H. Zhang, Z. Sun, W. Chen,
Y. Zhang, and H. Meng. 2013. Quantitative genetic background of the host influences gut microbiomes in chickens. Sci.Rep.3:1163;DOI:10.1038/srep01163.

Aksit, M., S. Yalcin, P. B. Siegel, C. Yenisey, D. Ozdemir, and S. Ozkan. 2013. Broilers respond to
cooler ambient temperatures after heat acclimation during incubation and early postnatal age. J. Appl. Poult. Sci. 22: 298-307.

Dunnington, E. A., C. F. Honaker, M. L. McGilliard, and P. B. Siegel. 2013. Phenotypic responses of
chickens to long-term, bidirectional selection for juvenile body weight – Historical perspective. Poult. Sci. 92: 1724-1734.

Ka, S., E. Markljung, H. Ring, F. W. Albert, M. Harun-Or-Rashid, P. Wahlberg, P. M. Garcia-Roves, J. R.
Zierath, D. M. Denbow, S. Paabo, P. B. Siegel, L. Andersson, and F. Hallbook. 2013. Expression of carnitine palmitoyl-CoA transferase-1B is influenced by a cis-acting eQTL in two chicken lines selected for high and low body weight. Physiol. Genomics 45: 367-376.

Siegel, P. B., and C. F. Honaker. 2013. Using long-term selection experiments in the molecular era. Proc.
8th European Poult. Genetics Sympos. 1-2. Venice, Italy.

Siegel, P. B., and C. F. Honaker. 2013. Poultry Breeding Strategies for Hot Climates. Proc. Int. Congr. On
Advancements in Poult. Prod. in the Middle East and African States. 16-21. Antalya, Turkey.

Ahsan, M., X. Li, A. E. Lundberg, M. Kierczak, P. B. Siegel, O. Carlborg, and S. Marklund. 2013.
Identification of candidate genes and mutations in QTL regions for chicken growth using bioinformatics analysis of NGS and SNP-chip data. Frontiers in Bioinformatics and Computational Biol. doi:10.3389/fgene.2013.00226.

    Paul Siegel

  • (540) 231-6472
  • (540) 231-3010 (Fax)
  • (540) 231-9189 (Lab)
  • pbsiegel@vt.edu
  • Animal and Poultry Sciences (0306)
    2170 Litton Reaves Hall, Virginia Tech
    175 West Campus Dr.
    Blacksburg, VA 24061